Healthcare Social Network. Share Knowledge, Be Discovered, Find Opportunities. Join Now
Eliquis | apixaban
Medication Class: Factor Xa Inhibitor
Manufacturer: Bristol Myers Squibb/Pfizer
Approval date: December 28, 2012
What is Eliquis and how does it work
Eliquis is an oral anticoagulant medication used to inhibit factor Xa. Inhibiting factor Xa blocks platelets from activating and fibrin clots from forming. It is similar to Xarelto.
What does Eliquis treat
Eliquis is used to prevent stroke and to reduce the risk of blockage of arteries in patients with nonvalvular atrial fibrillation which is an irregular heartbeat.
How effective is Eliquis
Eliquis 5 mg or 2.5 mg was found to be superior to warfarin in reducing the risk of stroke and embolism or clogging of arteries. The risk of stroke and embolism was 1.27% per year in patients treated with Eliquis and 1.6% per year in patients treated with warfarin. Bleeding was the most common adverse event for discontinuation of Eliquis. This occurred in 1.7% of patients who were on Eliquis and 2.5% in patients on warfarin. Patients who received Eliquis had a significantly lower risk of bleeding compared to warfarin treated patients.
What are interesting facts about Eliquis
How is Eliquis dosed and administered
Eliquis is an oral medication supplied as 2.5 mg and 5 mg tablet
For nonvalvular atrial fibrillation (stroke prevention), the recommended dose is 5 mg taken orally twice daily.
The recommended dose is 2.5 mg twice daily for patients with ≥ 2 of the following:
What are the side effects of Eliquis
Common: bruising, bleeding, nausea, anemia
Serious: severe allergic reactions, clinically significant active bleeding, gastrointestinal hemorrhage
Eliquis drug interactions
These drugs may increase the effect of Eliquis:
These drugs may decrease the affect of Eliquis:
-St. John’s wort
Drugs that may increase the risk of bleeding:
-Aspirin and other non-steroidal anti-inflammatory drugs (e.g., ibuprofen)
-Prozac (fluoxetine), Zoloft (sertraline) and other drugs that increase serotonin levels.
-Other drugs that increase bleeding
What is the cost of Eliquis
Per 5 mg tablet: $5.00
How to obtain prescription assistance for Eliquis
Visit the Bristol Myers Squibb prescription assistance website.
This medication summary is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.
Comment on this article or post an article by joining the RxEconsult community.
Please Share on Your Social Networks
More Articles by Kent Pham, PharmD