Bydureon | (exenatide extended release)
Medication class: Glucagon-like peptide-1 (GLP-1) receptor agonist
Manufactured by: Bristol Myers Squibb
Approval date: January, 2012
What is Bydureon and how does it work
Bydureon Injection is an extended-release (once weekly injection) formulation of Byetta (exenatide). It belongs to a group of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists because they resemble and mimic the action of human GLP-1 hormone (incretin hormone). They are also called incretin mimetics. It is an injectable drug that reduces blood glucose by increasing insulin production by the pancreas, slows the absorption of glucose from the gut, reduces the activity of glucagon (a hormone that increases release of glucose from the liver), and reduces appetite.
What does Bydureon treat
Type 2 diabetes mellitus in conjunction with diet and exercise. It is not used for treating type-1 diabetes or diabetic ketoacidosis and it should not be used in place of insulin when patients require insulin. It should also not be used as the first option in patients with type 2 diabetes whose blood glucose are not well controlled with diet and exercise.
How effective is Bydureon
What are interesting facts about Bydureon
What are the side effects of Bydureon
Common: Nausea, vomiting, diarrhea, constipation, headache, acid reflux, reduced appetite, stomach discomfort, and injection site reactions. The risk of hypoglycemia (low blood glucose) is increased when combined with a sulfonylurea.
Serious: Pancreatitis, serious allergic reactions, severely low blood glucose (hypoglycemia), kidney failure.
What is Bydureon dosage
Bydureon is available as a 2 mg vial of exenatide powder to be mixed with 0.65 ml diluent supplied in a pre-filled syringe. A Bydureon Pen is not currently available.
The recommended dose is 2 mg injected under the skin (thigh, abdomen, or upper arm) once weekly without regard to meal times.
Bydureon drug interactions
What is the price of Bydureon
Bydureon costs about $324 for a 4 week supply.
How to obtain prescription cost assistance for Bydureon
For prescription assistance visit:
Reference: Bydureon FDA Prescribing Information and medication Guide.
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This medication summary is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.