How effective is Herceptin for breast cancer treatment?
In a clinical study, 469 women with metastatic breast cancer who had not received treatment before were given chemotherapy alone or chemotherapy plus Herceptin 4 mg/kg followed by weekly doses of 2 mg/kg. Patients treated with a combination of chemotherapy and Herceptin had a higher response to therapy, longer time before disease progression, and better survival rates compared to patients treated with chemotherapy alone. The median survival rate was 25.1 months in 235 patients receiving Herceptin with their chemotherapy versus 20.3 months in 234 patients receiving chemotherapy alone.
Another study looked at 222 patients metastatic breast cancer who relapsed after treatment with one or two chemotherapy regimens. Patients were given a dose of 4 mg/kg IV followed by weekly doses of 2 mg/kg IV. The overall response rate was 14% with a 2% complete response rate and a 12% partial response rate.
Interesting Facts about Herceptin
What are side effects of Herceptin?
Serious side effects of Herceptin include:
Heart Problems such as congestive heart failure or reduced heart function