Seroquel | quetiapine
Medication Class: Atypical antipsychotic
Approval date: September 1997
What is Seroquel and how does it work
Seroquel is an atypical antipsychotic that theoretically works by reducing the effect of neurotransmitters (dopamine, serotonin) in the brain by blocking their receptors. It also blocks the effect of histamine.
What does Seroquel treat
How effective is Seroquel
What are interesting facts about Seroquel
How is Seroquel dosed (dosage) and administered
Seroquel tablets are administered orally with or without food.
Schizophrenia (Adult): 150-750 mg daily administered in 2 or 3 divided doses
Schizophrenia (adolescents): 400-800 mg daily administered in 2 or 3 divided doses.
Bipolar mania (adults): 400-800 mg daily in 2 divided doses.
Bipolar Mania (children and adolescents): 400-600 mg daily n 2 or 3 divided doses.
Bipolar depression: 300 mg daily at bedtime.
Bipolar disorder long-term treatment: 400-800 mg daily in 2 divided doses.
What are the side effects of Seroquel
Common: drowsiness, dry mouth, dizziness, constipation, stuffy nose, weight gain, increased liver enzymes, stomach upset, fatigue, increased appetite, nausea, vomiting, increased heart rate, low blood pressure when arising from a sitting or lying position, irritability, withdrawal symptoms (nausea, vomiting, insomnia), increased cholesterol, increased triglycerides.
Serious: increased blood glucose, diabetes, low blood pressure, fainting, neuroleptic, malignant syndrome, extrapyramidal symptoms, tardive dyskinesia (abnormal movement), low level of red and white blood cells, long and lasting painful erection, suicide, worsening depression, hypothyroidism, high blood pressure, seizure, severe low blood pressure, severe allergic reactions (anaphylaxis), abnormal heart beats or rhythm.
Seroquel drug interactions
What is the cost of Seroquel
Cost about $2 to $47 per tablet.
How to obtain prescription assistance for Seroquel
For prescription assistance for Seroquel visit Astrazeneca patient assistance program.
References: Seroquel FDA Prescribing Information and Medication Guide
Related Article: Seroquel XR medication monograph
This medication summary is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified healthcare provider.
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