What is Uloric (febuxostat), Side Effects, Dosage, Price, and Prescribing Information for Gout | Omudhome Ogbru, PharmD | RxEconsult

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Uloric (febuxostat) Uses, Side Effects, Dosage Category: Rheumatoid Arthritis & Inflammatory Conditions by - September 21, 2011 | Views: 9156 | Likes: 0 | Comment: 0  

Uloric | febuxostat

Medication Class: xanthine oxidase inhibitor
Manufacturer: Takeda Pharmaceuticals
Approval Date: February 2009

What is Uloric and how does it work

Uloric reduces blood uric acid levels by blocking the activity of xanthine oxidase, an enzyme that converts proteins to uric acid. Uloric is also classified as a xanthine oxidase inhibitor.

What is Uloric used for

Uloric is used for reducing blood uric acid levels in adults with gout.

How effective is Uloric

  • Uloric 80 mg reduced uric acid levels to less than 6 mg/dl in 67 to 74% of patients. Only 36 to 42% of patients that received allopurinol achieved similar levels in clinical studies.
  • In 76% of patients treated with Uloric 80 mg daily, uric acid levels decreased to less than 6 mg per dL within 2 Weeks of treatment.

What are interesting facts about Uloric

  • Uloric was more effective than allopurinol in clinical studies.
  • Dosage adjustment is not required for patients with mild or moderate reduction in kidney function.

What is the dosage of Uloric and administration

40 or 80 mg orally, once daily without regard to meals.

What are the side effects of Uloric

Common: Abnormal liver function tests, nausea, joint pain, rash, gout flare

Serious: Stroke, heart attack, hypersensitivity reactions, rhabdomyolysis (muscle breakdown)

Uloric drug interactions


What is the price of Uloric

30 tablets of Uloric cost $212 (average wholesale price)

How to obtain prescription assistance for Uloric

For prescription assistance for Uloric visit Takeda Prescription Assistance Program.

References: Uloric FDA Prescribing Information.


The material on this site is for information only and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.


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