Vyvanse (lisdexamfetamine) Cost, Side Effects, Dosage for ADHD in Adults or Children, and Binge Eating Disorder (BED) | Sahar Anjomshoaa, PharmD | RxEconsult

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Vyvanse (lisdexamfetamine dimesylate) Cost, Side Effects, Dosage, and Prescribing Information for ADHD and Binge Eating Category: ADHD, Autism, Seizures, by - November 7, 2014 | Views: 40245 | Likes: 0 | Comment: 0  

What are Vyvanse drug interactions?

Combining monoamine oxidase inhibitors (e.g., selegiline, rasagiline) with Vyvanse may cause a severe increase in blood pressure. Vyvanse should not be given with MAOIs or within 14 days after discontinuation of MAOIs. A similar reaction may occur with Linezolid. 

Ascorbic acid and other agents that acidify urine increase excretion of Vyvanse in urine. Sodium bicarbonate and other agents that alkalinize urine decrease excretion of Vyvanse through urine. 

Selective serotonin reuptake inhibitors (SSRI) or Serotonin-norepinephrine reuptake Inhibitors (SNRI) such as fluoxetine, venlafaxine, citalopram, escitalopram when given with Vyvanse can increase serotonin levels and cause serious interactions.

What are warnings and precautions for Vyvanse?

Serious cardiovascular reactions including stroke, heart attack, increased blood pressure, and myocardial infarction may occur. Avoid use in patients with cardiovascular problems.

Suppression of growth, including a reduction in height and weight, may occur in children. Monitoring height and weight during treatment is recommended.

Vyvanse may increase the risk of psychosis or manic symptoms in bipolar patients. Discontinue Vyvanse immediately if such reactions occur. 

Pregnancy: Vyvanse has not been adequately studied in pregnant women. Premature delivery and low birth weight have occurred in infants born to mothers dependent on amphetamines. 

Nursing Mother: Vyvanse is excreted into human milk and can cause serious adverse reactions. It is not recommended for nursing mothers.

Pediatric use: There is no data for use in treating ADHD in children less than 6 years old. 

What is the cost of Vyvanse?

The wholesale price for 100 capsules of Vyvanse 30 mg is $663.41 and the retail price is approximately $726.96.

How to obtain prescription cost assistance for Vyvanse?

For prescription assistance for Vyvanse visit The Shire patient assistance program.


Vyvanse, Prescribing Information, Shire, July 2014

RedBook Online, Vyvanse, Truven Health Analytics, Inc.;2014


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