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Ebola Virus Outbreak: Symptoms, Treatment, and Prevention of Ebola Hemorrhagic Fever Category: Viral Infections by - August 14, 2014 | Views: 34279 | Likes: 3 | Comment: 0  

Ebola Virus Outbreak

By Brea Edherue

Ebola Outbreak

Alarm, confusion, and fear fill the air in many American homes as the second American diagnosed with Ebola arrived on US soil this past week. Many citizens are wondering if it is possible that these two infected citizens could infect the rest of the general population. This Ebola outbreak is causing mass confusion. However this is not the first Ebola outbreak to affect the world’s population.

The first Ebola outbreaks occurred in the late 1970s in South Sudan, and the Democratic Republic of Congo. Since the 1970s the Ebola virus has remained relatively localized. Outbreaks of the Ebola virus are mainly concentrated in Western Africa affecting over 1,603 people. Of the 1,603 people that were infected, there were 887 deaths, giving the Ebola virus a death rate of over 50%. Death rates in other regions are higher. There are no approved medications or vaccines for treating or preventing Ebola virus infections, which makes it even more dangerous. Many experts are expecting death rates from Ebola to rise. 

Transmission of Ebola 

Ebola is a relatively new virus, but it is an exotic disease. There are five different Ebola strains, but only four are known to cause severe illness in both humans and animals. Although Ebola is infectious it is not highly contagious. Ebola is not airborne and therefore it is not easily transmitted as other illnesses such as influenza, making it a moderately contagious disease. Those at the highest risk for infection include healthcare workers, and family and friends who care for infected persons. 

Over 10 countries in Africa have confirmed cases of Ebola hemorrhagic fever (Ebola HF) since the virus was first discovered. These countries include: 

  • Guinea
  • Liberia
  • Sierra Leone
  • Nigeria
  • Democratic Republic of Congo
  • Gabon
  • South Sudan
  • Ivory Coast
  • Uganda
  • Republic of Congo
  • South Africa. 

The natural reservoir of the Ebola virus has not been discovered. Generally Ebola is transmitted from human to human and from animal to human. The Ebola virus is transmitted when a non-infected person comes into contact with an infected person's bodily fluids, contaminated objects such as needles, and also from butchering infected animals. The Ebola virus known is spread in close quarters from friends and families caring for infected persons. Outbreaks can spread rapidly in close setting such as hospitals, schools, and other healthcare settings. It is important to maintain good hygiene when caring for infected individuals or coming into contact with any infected person. 

Signs and Symptoms of Ebola Infection 

Symptoms of the Ebola virus often mimic other diseases such as malaria, typhoid fever, hepatitis, plague, and other hemorrhagic fevers. Laboratory tests are required to accurately diagnose Ebola. 

Symptoms of Ebola infection include: 

  • Sudden onset of fever
  • Intense weakness
  • Diarrhea
  • Rash
  • Muscle pain
  • Impaired kidney and liver function
  • Possible internal bleeding and external bleeding

Treatment of Ebola

There are no approved antiviral medications or vaccines for treatment of Ebola. Severely ill patients require intensive supportive care and monitoring. They are often dehydrated and require rehydration and electrolyte replacement treatments. 

An experimental drug was recently cleared to be used in infected patients even though it has not been approved. Authorities believe it is ethical to use an experimental drug because Ebola is so deadly. The drug is called ZMapp and it is developed by Mapp Biopharmaceutical. It is an antibody that prevents replication of the Ebola virus. It has slowed the severity of the disease in those who have received it.  

Prevention of Ebola Outbreak

Uncertainty about the natural Ebola reservoir presents a challenge in establishing primary prevention protocols. One prevention strategy measure includes barrier-nursing techniques for healthcare workers such as wearing protective clothing, masks, gloves, gown, and goggles. It also includes isolation of Ebola HF patients, sterilizing equipment, and avoiding contact with deceased patients. 

The Center for Disease Control (CDC) and the World Healthcare Organization have developed resources for healthcare facilities to help them recognize Ebola HF, and prevent further transmission by using readily available materials. 

References & Resources

Centers for Disease Control and Prevention: About Ebola Hemorrhagic Fever

 CDC Ebola Hemorrhagic Fever Fact Sheet

Brea Edherue is a Health Administration and Public Policy graduate from UMBC. She currently works at a private health company and plans to pursue a master’s degree in health administration. 

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