
Brand Name: Jardiance
Generic Name: empagliflozin
Medication Class: SGLT-2 Inhibitor
Similar Drugs: Invokana (canagliflozin), Farxiga (dapagliflozin)
Manufacturer: Boehringer Ingelheim
Approval Date: August 2014
What is Jardiance and its mechanism of action?
Jardiance (empagliflozin) is an oral medication that decreases blood glucose (sugar) in people with diabetes by blocking the kidney from reabsorbing glucose and removing excess glucose through the urine. It does this by blocking the sodium-glucose co-transporter-2 (SGLT2) which is a protein in the kidney that is responsible for reabsorbing glucose back into the body. Lowering high blood glucose can help prevent nerve problems, blindness, and kidney damage in people with diabetes. Proper control of blood glucose can also decrease the risk of getting a heart attack or stroke.
What is Jardiance used for?
To reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease. (new indication 12/2/2016)
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