Brand Name: Jardiance
Generic Name: empagliflozin

Medication Class: SGLT-2 Inhibitor
Similar Drugs: Invokana (canagliflozin), Farxiga (dapagliflozin)
Manufacturer: Boehringer Ingelheim
Approval Date: August 2014

What is Jardiance and its mechanism of action?

Jardiance (empagliflozin) is an oral medication that decreases blood glucose (sugar) in people with diabetes by blocking the kidney from reabsorbing glucose and removing excess glucose through the urine. It does this by blocking the sodium-glucose co-transporter-2 (SGLT2) which is a protein in the kidney that is responsible for reabsorbing glucose back into the body. Lowering high blood glucose can help prevent nerve problems, blindness, and kidney damage in people with diabetes. Proper control of blood glucose can also decrease the risk of getting a heart attack or stroke.

What is Jardiance used for?

• Jardiance is used in addition to exercise and diet to lower fasting and postprandial (after a meal) blood glucose levels in patients with type 2 diabetes.

• To reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease. (new indication 12/2/2016) 

Next: Effectiveness, Facts, Side Effects

Read: Effect Of Jardiance (empagliflozin) On Heart Attacks, Strokes, And Death In People With Type 2 Diabetes