Introduction

Recognized by the World Health Organization as the fourth leading cause of disability and death in the world as of 2001, depression is a major, multi-modal disorder that affects a person’s mood, physical health, and behavior. It has been reported that as of the year 2020, Major Depressive Disorder (MDD) will be the second leading burden of disease — behind ischemic heart disease. Consequently, it is vital for researchers and clinicians to treat adequately this illness and mitigate its manifestations.

There are several antidepressants available on the market today. Since all available antidepressants are effective, side effects of these medications are important distinguishing factors and are often used to select the most appropriate agent for a patient. This topic is very pertinent considering the frequency with which these medications are prescribed.

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